• Post-tick symptoms: persistent symptoms following known or suspected tick exposure.
• Febrile illness: recurrent or unexplained fever episodes.
• Fatigue: ongoing tiredness or reduced stamina.
• Musculoskeletal symptoms: muscle aches, joint pain or stiffness.
• Neurological symptoms: headaches, cognitive changes or sensory disturbances.
• Immune-related symptoms: fluctuating or reduced immune resilience.
• Atypical Lyme-like symptoms: symptoms not fully explained by standard Borrelia testing.
• Immune assessment context: limited insight from antibody-based testing alone.

Overview

The Borrelia miyamotoi EliSpot test measures T-cell mediated immune responses to Borrelia miyamotoi using an ELISPOT laboratory method from a blood sample. This cellular immune approach focuses on T-cell activity rather than antibody production, offering insight into immune recognition of this tick-borne organism.

This test may be clinically useful when symptoms or exposure history raise questions around Borrelia miyamotoi and antibody-based testing has provided limited or unclear information. Cellular immune assessment can add context where humoral antibody responses are absent, delayed or difficult to interpret.

Practitioners typically interpret results alongside clinical history, symptom patterns, tick exposure risk, travel history and other relevant laboratory investigations. Reviewing these factors together supports informed discussions with clients about immune response patterns and further investigative considerations.

Practical

Practical

Specimen requirements:

 1x CPDA blood tube