- Menopausal symptoms: hot flushes, night sweats, mood changes or vaginal dryness.
- PMS or cycle related symptoms: irritability, breast tenderness or irregular menstrual cycles.
- Androgen related symptoms: acne, increased facial or body hair or reduced libido.
- Low libido or sexual function concerns: changes in desire or performance in men or women.
- Energy and stamina concerns: ongoing fatigue, low motivation or reduced physical endurance.
- Sleep disturbances: insomnia, early waking or unrefreshing sleep.
- Weight changes: unexplained weight gain or difficulty maintaining weight.
- Blood sugar related symptoms: energy dips, cravings or fluctuating appetite.
- Stress related symptoms: feeling overwhelmed, irritable or experiencing reduced stress tolerance.
- Mood related symptoms: anxiety, irritability or low mood.
- Cognitive changes: reduced mental sharpness, forgetfulness or reduced concentration.
- Prostate related symptoms in men: urinary changes or enlarged prostate monitored by a practitioner.
Overview
The Comprehensive Hormone Profile measures a selection of sex hormones and four cortisol collections across the day using saliva samples, offering insight into both reproductive hormone balance and hypothalamic pituitary adrenal (HPA) axis patterns. The panel includes oestradiol, progesterone, testosterone, DHEA and diurnal cortisol, and also calculates the progesterone to estradiol ratio to illustrate hormonal relationships.
Clinically, this assessment may be useful when exploring symptoms related to menopause, menstrual cycle irregularities, andropause, libido, mood, sleep, stress tolerance or changes in weight and energy. Measuring hormones in saliva reflects the bioavailable fraction, which may help practitioners understand how hormones are functioning at the tissue level. The diurnal cortisol curve adds additional context by illustrating variations in cortisol secretion across the day.
Practitioners often combine these findings with health history, lifestyle factors, nutritional considerations and other hormone or metabolic tests. Used in this way, the Comprehensive Hormone Profile can support personalised discussions and help contextualise clients' experiences within a broader assessment.
Practical
Sample required:
Saliva