Women:

• Fatigue or low energy: Persistent tiredness or reduced stamina.
• Low mood or depression: Changes in emotional wellbeing or motivation.
• Reduced libido: Decline in sexual desire or satisfaction.
• Premenstrual symptoms: PMS, irritability or mood changes before menstruation.
• Menopausal transition: Menopause-related changes such as sleep disruption or hot flushes.
• Weight gain: Gradual or unexplained weight increase.

Men:

• Fatigue or low energy: Ongoing tiredness or reduced physical drive.
• Low mood or depression: Persistent low mood or reduced motivation.
• Reduced sex drive: Lower libido or changes in sexual performance.
• Sleep disturbance: Difficulty falling asleep or staying asleep.
• Hair loss: Thinning hair or changes in hair pattern.
• Weight gain: Increased abdominal or overall body weight.

Overview

DUTCH Sex Hormone Metabolites measures a broad range of sex hormone metabolites using dried urine samples analysed by GC-MS/MS technology. The test focuses on oestrogen, progesterone and androgen metabolites, with results normalised to creatinine to provide values that correlate with 24-hour urine collections without requiring full-day sampling.

This test may be clinically useful when practitioners want a detailed view of sex hormone metabolism rather than single-point hormone levels. It allows observation of relative hormone production patterns and metabolite balance, which may relate to mood, energy, body composition or reproductive life stage.

Practitioners typically review results alongside symptom history, age, sex, menstrual status, lifestyle factors and other laboratory findings. Patterns are interpreted in context to support informed discussions with clients, including baseline assessment or ongoing monitoring where appropriate.

Practical

Practical

Sample type:

Dried urine

Average processing time:

Maximum of 21 days