• Oxidative stress concerns: clients with symptoms or histories associated with increased oxidative load.
• Metabolic and glucose related conditions: metabolic syndrome, diabetes related complications or fluctuating blood sugar patterns.
• Neurological and cognitive conditions: Parkinson’s, Alzheimer’s, Huntington’s or practitioner-monitored neurodegenerative concerns.
• Inflammatory or immune-related conditions: rheumatoid arthritis, atopic dermatitis, inflammatory bowel conditions or chronic hepatitis.
• Chronic disease context: cancer, pancreatitis, cystic fibrosis or other long-term conditions under practitioner review.
• Environmental exposure concerns: suspected contact with pollutants, toxic metals, chemicals or smoke.
• Skin or tissue integrity concerns: irritation, inflammation or chronic tissue stress.
• General fatigue or low stamina: persistent tiredness or reduced resilience potentially linked with oxidative processes.

Overview

The Oxidative Damage test measures urinary 8-hydroxy-2'-deoxyguanosine using an enzyme immunoassay (EIA) to provide a quantitative marker of DNA oxidation. This biomarker reflects oxidative stress processes in the body, with 8-OHdG representing one of the most frequently detected oxidative modifications of DNA excised during cellular repair and excreted in urine.

Clinically, this assessment may be useful when exploring oxidative stress in the context of metabolic conditions, chronic inflammation, neurodegenerative concerns, long-standing disease processes or environmental exposures. Elevated oxidative damage has been examined in research relating to a wide range of chronic conditions, making 8-OHdG a practical marker for practitioners considering the relationship between oxidative balance and presenting symptoms.

Practitioners typically interpret these findings alongside dietary patterns, lifestyle influences, environmental contact, antioxidant intake and other functional biomarkers. Used in this way, the Oxidative Damage test can help inform conversations about oxidative stress patterns, nutritional considerations and long-term wellbeing strategies for clients.

Practical

Sample required:

Urine (FMV)

Average processing time:

Maximum of 3 weeks