• Recurrent oral symptoms: cold sores or lip lesions that recur over time.
• Genital symptoms: recurrent genital or rectal sores or irritation.
• Post-viral symptoms: lingering symptoms following a suspected viral episode.
• Neurological symptoms: nerve-related pain, tingling or sensory changes.
• Fatigue and low energy: ongoing tiredness not explained by lifestyle factors.
• Immune-related symptoms: reduced immune resilience or frequent viral flare patterns.
• Atypical presentation: symptoms with limited clarity from antibody testing alone.
• Exposure history: known or suspected exposure without consistent antibody findings.

Overview

The Herpes Simplex (HSV) I & II EliSpot test measures T-cell mediated immune responses to HSV-1 and HSV-2 using an ELISPOT laboratory method from a blood sample. This cellular immune approach focuses on T-cell activity rather than antibody production, offering insight into immune recognition at the cellular level.

This test may be clinically useful when symptoms or history raise questions around HSV exposure and antibody-based testing has provided limited or inconsistent information. Assessing cellular immune response can add context where humoral antibody responses do not fully reflect immune activity.

Practitioners typically interpret results alongside clinical history, symptom patterns, prior viral exposure, sexual health history where relevant and other immune-related laboratory findings. This broader perspective supports informed discussions with clients about immune response patterns and further investigative considerations.

Practical

ACD/CPDA

This sample requires a blood draw